Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866298 | 0.90 | DHODH (0.82) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL42477 | 0.90 | DHODH (0.81) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29788461 | 0.90 | DHODH (0.81) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8240361 | 0.88 | DHODH (0.70) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14708680 | 0.85 | SMN1; SMN2 (0.70) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13056561 | 0.85 | DHODH (0.71) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL20118104 | 0.85 | DHODH (0.67) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29674931 | 0.85 | RAB9A (0.70) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4602056 | 0.85 | RAB9A (0.70) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3009696 | 0.84 | POLB (0.74) | DHODHKDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071987-A | Quinoline dyes; colorfastness | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |