Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438136 | 0.76 | — | — | |
| SCHEMBL151133 | 0.75 | — | — | |
| SCHEMBL11406123 | 0.75 | CHRNB2 (0.40) | TSHR | |
| SCHEMBL19999959 | 0.74 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL11036343 | 0.73 | LOX (0.32) | TSHR | |
| SCHEMBL11144102 | 0.72 | ALDH1A1 (0.47) | TSHRTHRB | |
| SCHEMBL1188228 | 0.72 | ALDH1A1 (0.47) | TSHRTHRB | |
| SCHEMBL28584833 | 0.72 | ALDH1A1 (0.47) | TSHRTHRB | |
| SCHEMBL11370525 | 0.71 | TSHR (0.34) | TSHR | |
| SCHEMBL6161515 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |