Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865595 | 0.73 | PSMB8 (0.38) | PSMB8MAPK1MCL1KDM4EALDH1A1 | |
| SCHEMBL9016796 | 0.69 | GRIA4 (0.45) | GRIA4MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL8494974 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31568860 | 0.67 | MAPK1 (0.53) | PSMB8MAPK1MCL1KDM4EALDH1A1 | |
| SCHEMBL9788746 | 0.66 | KDM4E (0.43) | PSMB8MAPK1MCL1KDM4EALDH1A1 | |
| SCHEMBL10654269 | 0.65 | ALDH1A1 (0.47) | GRIA4KDM4EALDH1A1MAPTMEN1 | |
| Dichlobenil SCHEMBL55606 | 0.64 | ALDH1A1 (0.55) | PSMB8MAPK1KDM4EALDH1A1MAPT | |
| Dichlobenil SCHEMBL1701380 | 0.64 | ALDH1A1 (0.55) | PSMB8MAPK1KDM4EALDH1A1MAPT | |
| Dichlobenil SCHEMBL10737856 | 0.62 | ALDH1A1 (0.53) | PSMB8MAPK1KDM4EALDH1A1MAPT | |
| Dichlobenil SCHEMBL28232070 | 0.62 | ALDH1A1 (0.53) | PSMB8MAPK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |