Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865808 | 0.73 | PSMB8 (0.43) | PSMB8KDM4EMAPK1MCL1OGG1 | |
| SCHEMBL9016795 | 0.71 | ALDH1A1 (0.36) | KDM4EMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL10658430 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL9865724 | 0.66 | MEN1 (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL10651774 | 0.66 | ALDH1A1 (0.38) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31568860 | 0.65 | MAPK1 (0.53) | PSMB8KDM4EMAPK1MCL1OGG1 | |
| SCHEMBL9865016 | 0.64 | FNTA (0.39) | KDM4EMAPK1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL9788746 | 0.64 | KDM4E (0.43) | PSMB8KDM4EMAPK1MCL1OGG1 | |
| SCHEMBL9865502 | 0.63 | ALDH1A1 (0.43) | KDM4EMAPK1ALDH1A1NPSR1 | |
| Dichlobenil SCHEMBL55606 | 0.62 | ALDH1A1 (0.55) | PSMB8KDM4EMAPK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |