Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602830 | 0.92 | HRH3 (0.48) | HRH3ACHEHTR1A | |
| SCHEMBL9601558 | 0.91 | MAOB (0.46) | HRH3ACHEHTR1AHTR7HTR6 | |
| SCHEMBL9866888 | 0.84 | MAPT (0.41) | HRH3 | |
| Hydrochloric Acid SCHEMBL9602451 | 0.77 | MAPK14 (0.46) | HRH3HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9602446 | 0.77 | MAPK14 (0.46) | HRH3HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9865627 | 0.76 | HRH3 (0.46) | HRH3 | |
| Hydrochloric Acid SCHEMBL9865621 | 0.76 | HRH3 (0.46) | HRH3 | |
| Hydrochloric Acid SCHEMBL9866019 | 0.76 | DRD2 (0.44) | HRH3 | |
| Hydrochloric Acid SCHEMBL9866011 | 0.76 | DRD2 (0.44) | HRH3 | |
| Maleic Acid SCHEMBL9602897 | 0.75 | HRH3 (0.44) | HRH3ACHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |