Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESPL1 | Q14674 | 2/20 | 0.42 |
| ▸ | TLR3 | O15455 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767527 | 1.00 | ESPL1 (0.42) | ESPL1TLR3SMN1; SMN2HPGDLMNA | |
| SCHEMBL9767521 | 1.00 | ESPL1 (0.42) | ESPL1TLR3SMN1; SMN2HPGDLMNA | |
| SCHEMBL9767103 | 0.88 | TLR3 (0.39) | ESPL1TLR3SMN1; SMN2LMNAHTT | |
| SCHEMBL9767111 | 0.88 | TLR3 (0.39) | ESPL1TLR3SMN1; SMN2LMNAHTT | |
| SCHEMBL9767097 | 0.88 | TLR3 (0.39) | ESPL1TLR3SMN1; SMN2LMNAHTT | |
| SCHEMBL8135764 | 0.83 | TLR3 (0.37) | TLR3SMN1; SMN2LMNAHTTAKR1B1 | |
| SCHEMBL9767136 | 0.81 | AKR1B1 (0.40) | TLR3SMN1; SMN2LMNAHTTAKR1B1 | |
| SCHEMBL9767134 | 0.81 | AKR1B1 (0.40) | TLR3SMN1; SMN2LMNAHTTAKR1B1 | |
| SCHEMBL9767130 | 0.81 | AKR1B1 (0.40) | TLR3SMN1; SMN2LMNAHTTAKR1B1 | |
| SCHEMBL9767647 | 0.80 | ESPL1 (0.43) | ESPL1TLR3SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072006-A | Chemical intermeidate; hypotensive agents, muscle relaxants | RECHERCHE SYNTEX FRANCE S.A. (FR) | 1991-12-10 | — | — | US | disclosed |
| EP-0377966-A2 | Novel benzopyranylpyrrolinone derivatives | RECHERCHE SYNTEX FRANCE SA (FR) | 1990-07-18 | — | — | EP | disclosed |