Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876878 | 0.90 | CYSLTR2 (0.52) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9865792 | 0.87 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 | |
| SCHEMBL7717113 | 0.80 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 | |
| Water SCHEMBL9719934 | 0.79 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 | |
| SCHEMBL9604332 | 0.77 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 | |
| SCHEMBL7454127 | 0.76 | CYSLTR1 (0.63) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 | |
| SCHEMBL9876648 | 0.76 | CYSLTR2 (0.60) | CYSLTR1CYSLTR2MEN1LMNATP53 | |
| SCHEMBL8416340 | 0.76 | CA9 (0.63) | NPC1LMNAMAPT | |
| SCHEMBL9865885 | 0.75 | GPBAR1 (0.57) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10755026 | 0.75 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045547-A | Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |