Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 7/20 | 0.63 |
| ▸ | CA1 | P00915 | 6/20 | 0.63 |
| ▸ | CA2 | P00918 | 6/20 | 0.63 |
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
| ▸ | IDH1 | O75874 | 5/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415189 | 0.88 | CA1 (0.62) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL8416302 | 0.86 | CA12 (0.61) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL2303216 | 0.85 | LMNA (0.63) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL9487024 | 0.83 | CA12 (0.60) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL7774865 | 0.82 | CA1 (0.59) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL9435949 | 0.82 | CA1 (0.62) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL6331212 | 0.81 | CA1 (0.61) | CA9CA1CA2CA12FBP1 | |
| SCHEMBL8726381 | 0.80 | FBP1 (0.58) | CA9CA1CA2CA12FBP1 | |
| SCHEMBL6326503 | 0.80 | CA1 (0.55) | CA9CA1CA2CA12IDH1 | |
| SCHEMBL8415196 | 0.79 | FBP1 (0.54) | CA9CA1CA2CA12FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990353-A | DEMETALLIZING AN ARYLSULFONAMIDE ALKALI METAL SALT WITH AN AROMATIC ISOCYANATE COMPOUND IN AT LEAST ONE SOLVENT; USE AS A COLOR DEVELOPER FOR A THERMAL RECORDING MATERIAL WITH IMPROVED OIL RESISTANCE AND NONPLASTICIZED | YAMAMOTO CHEMICALS, INC. (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0879816-A1 | Process for producing arylsulfonylureide compounds | Yamamoto Chemicals, Inc. (JP) | 1998-11-25 | — | — | EP | disclosed |