Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | UTRN | P46939 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868637 | 0.85 | SMN1; SMN2 (0.45) | PTPN1PTPN2PTPN5HSPD1HSPE1 | |
| SCHEMBL9868913 | 0.78 | NPC1 (0.46) | CETPHDAC6NPC1RAB9AALDH1A1 | |
| SCHEMBL30788998 | 0.76 | CETP (0.51) | CETPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9867163 | 0.75 | NPC1 (0.66) | PTPN1PTPN2PTPN5HSPD1HSPE1 | |
| SCHEMBL22259813 | 0.73 | MAPT (0.42) | — | |
| SCHEMBL25026542 | 0.72 | HDAC3 (0.60) | CETPHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31631303 | 0.72 | NPC1 (0.64) | IKBKBHSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL24038157 | 0.72 | NPC1 (0.57) | HSD17B10NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30648212 | 0.71 | CHRNA7 (0.47) | S1PR1S1PR3HTTHSD17B10NPC1 | |
| SCHEMBL27075892 | 0.71 | CHRNA7 (0.47) | S1PR1S1PR3HTTHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |