Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866308 | 0.85 | CETP (0.43) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL9868913 | 0.85 | NPC1 (0.46) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL22259813 | 0.80 | MAPT (0.42) | MAOAADRA1AMAPTRXFP1TP53 | |
| SCHEMBL31631303 | 0.79 | NPC1 (0.64) | SMN1; SMN2ALDH1A1HPGDKDM4ENFKB1 | |
| SCHEMBL27075892 | 0.78 | CHRNA7 (0.47) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30648212 | 0.78 | CHRNA7 (0.47) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9868181 | 0.77 | NPC1 (0.71) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL9867554 | 0.76 | NPC1 (0.50) | SMN1; SMN2ALDH1A1HPGDKDM4ENFKB1 | |
| SCHEMBL9374831 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL9374824 | 0.75 | KDM4E (0.44) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |