Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188130 | 0.85 | MCL1 (0.51) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL21807358 | 0.84 | MCL1 (0.57) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL18358089 | 0.84 | MCL1 (0.50) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL11600616 | 0.75 | MCL1 (0.53) | MCL1DAOKMT2APHGDHMEN1 | |
| SCHEMBL31291305 | 0.75 | MCL1 (0.53) | MCL1DAOKMT2APHGDHMEN1 | |
| SCHEMBL9868488 | 0.74 | MCL1 (0.57) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL27852170 | 0.74 | MCL1 (0.57) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL28360338 | 0.73 | MCL1 (0.46) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL10514487 | 0.72 | MCL1 (0.48) | MCL1DAOKMT2ANPC1RAB9A | |
| SCHEMBL13354733 | 0.72 | KMT2A (0.49) | MCL1DAOKMT2APHGDHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |