Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GCG | P01275 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | LDLR | P01130 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335832 | 0.83 | HDAC3 (0.57) | HTTHDAC3SMN1; SMN2ALDH1A1SELL | |
| SCHEMBL9866534 | 0.80 | GAA (0.46) | HTTHDAC3SMN1; SMN2ALDH1A1GCG | |
| SCHEMBL9335895 | 0.76 | CASR (0.43) | HTTHDAC3POLBCASRITGB3 | |
| SCHEMBL2523349 | 0.73 | CASR (0.65) | POLBLMNACASRALDH1A1SELL | |
| Formic Acid SCHEMBL9339307 | 0.73 | CASR (0.43) | HTTHDAC3POLBCASRCA1 | |
| SCHEMBL14426473 | 0.72 | SELL (0.65) | POLBSMN1; SMN2LMNACASRALDH1A1 | |
| SCHEMBL12200789 | 0.71 | CA1 (0.52) | HDAC3POLBSMN1; SMN2LMNACA1 | |
| SCHEMBL14426833 | 0.70 | SELL (0.62) | HDAC3POLBSMN1; SMN2LMNACASR | |
| SCHEMBL14054114 | 0.69 | CA1 (0.54) | POLBSMN1; SMN2LMNAALDH1A1CA1 | |
| SCHEMBL9339460 | 0.69 | NPC1 (0.59) | HTTHDAC3SMN1; SMN2ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |