Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335895 | 0.96 | CASR (0.43) | CASRITGB3ITGAVLNPEPERAP2 | |
| Formic Acid SCHEMBL9335859 | 0.89 | POLB (0.48) | CASRLNPEPERAP2POLB | |
| SCHEMBL9337573 | 0.84 | POLB (0.52) | LNPEPERAP2POLBHTT | |
| Formic Acid SCHEMBL9339344 | 0.83 | EPHX2 (0.44) | CASRITGB3ITGA2B | |
| SCHEMBL9335939 | 0.79 | HDAC3 (0.39) | ITGB3LNPEPERAP2HDAC3ITGA2B | |
| SCHEMBL9335651 | 0.79 | EPHX2 (0.47) | CASRITGB3ITGA2B | |
| SCHEMBL9337587 | 0.75 | HPGD (0.40) | ITGB3LNPEPERAP2POLBHDAC3 | |
| SCHEMBL9866523 | 0.73 | HTT (0.49) | CASRITGB3ITGAVPOLBHDAC3 | |
| SCHEMBL177287 | 0.72 | CASR (0.62) | CASRLNPEPERAP2 | |
| SCHEMBL177286 | 0.72 | CASR (0.62) | CASRLNPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | claimed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |