Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822152 | 0.76 | TDP1 (0.46) | TDP1HTR6ALDH1A1KDM4EHPGD | |
| SCHEMBL10649910 | 0.76 | TDP1 (0.43) | TDP1RECQLHTR6ALDH1A1HTT | |
| SCHEMBL9865416 | 0.76 | TDP1 (0.43) | TDP1RECQLHTR6ALDH1A1HTT | |
| SCHEMBL9865353 | 0.75 | RECQL (0.39) | RECQLHTR6ALDH1A1HTTKDM4E | |
| SCHEMBL2488614 | 0.74 | RECQL (0.61) | TDP1RECQLALDH1A1HTTKDM4E | |
| SCHEMBL19194357 | 0.70 | TDP1 (0.39) | TDP1RECQLHTR6ALDH1A1HTT | |
| SCHEMBL9821991 | 0.68 | TDP1 (0.38) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9822041 | 0.67 | KMT2A (0.44) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9822045 | 0.66 | TDP1 (0.33) | TDP1RECQLALDH1A1HTT | |
| SCHEMBL9821928 | 0.66 | RECQL (0.50) | RECQLALDH1A1HTTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013351-A | Triazolo-pyrimidine-2-sulphonamides useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0268951-A2 | Triazolopyrimidine-2-sulphone amides | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |