Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649910 | 0.86 | TDP1 (0.43) | TDP1HTR6TSHRLMNAALDH1A1 | |
| SCHEMBL9830595 | 0.79 | TSHR (0.44) | TSHRLMNAALDH1A1USP2KDM4E | |
| SCHEMBL1742675 | 0.78 | LMNA (0.53) | TSHRLMNAALDH1A1USP2KDM4E | |
| SCHEMBL9865614 | 0.77 | TSHR (0.48) | TDP1HTR6TSHRLMNAALDH1A1 | |
| SCHEMBL9866533 | 0.76 | TDP1 (0.41) | TDP1HTR6TSHRALDH1A1KDM4E | |
| SCHEMBL10562451 | 0.74 | TDP1 (0.33) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9866247 | 0.73 | PKM (0.34) | TSHRALDH1A1KDM4EHSD17B10RECQL | |
| SCHEMBL9593956 | 0.71 | MEN1 (0.40) | TSHRLMNAALDH1A1USP2KDM4E | |
| SCHEMBL10490335 | 0.70 | ALDH1A1 (0.45) | TSHRLMNAALDH1A1USP2KDM4E | |
| SCHEMBL10415912 | 0.68 | NPC1 (0.42) | TDP1TSHRALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013351-A | Triazolo-pyrimidine-2-sulphonamides useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0268951-A2 | Triazolopyrimidine-2-sulphone amides | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |