Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866936 | 0.87 | TOP1 (0.43) | TSHRALDH1A1KDM4EGAATOP1 | |
| SCHEMBL9867838 | 0.83 | KDM4E (0.53) | TSHRALDH1A1KDM4EGAARAB9A | |
| SCHEMBL9866994 | 0.82 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EGAARAB9A | |
| SCHEMBL9868777 | 0.82 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8174987 | 0.78 | CES2 (0.57) | ALDH1A1KDM4ECES2CES1ESR1 | |
| SCHEMBL10529004 | 0.76 | TSHR (0.47) | TSHRALDH1A1KDM4EGAARAB9A | |
| SCHEMBL9867546 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EGAARAB9A | |
| SCHEMBL8871264 | 0.74 | NPC1 (0.35) | TSHRALDH1A1KDM4ERAB9ACES2 | |
| SCHEMBL9867553 | 0.74 | CHRM2 (0.41) | TSHRALDH1A1KDM4EGAARAB9A | |
| SCHEMBL7658156 | 0.74 | TSHR (0.51) | TSHRALDH1A1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001121-A | Cephalosporin compounds and pharmaceutical compositions thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0197409-B1 | CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4956474-A | PHTHALIMIDOOXY OR AMINOXY COMPOUNDS FOR MAKING CEPHALOSPORINS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0360298-A2 | Intermediate compounds for use in the synthesis of cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0359291-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4904791-A | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4840945-A | ANTIBIOTICS EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0266060-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-05-04 | — | — | EP | disclosed |
| EP-0197409-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-15 | — | — | EP | disclosed |
| WO-1986005786-A1 | CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |