Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 3/20 | 0.66 |
| ▸ | F3 | P13726 | 3/20 | 0.66 |
| ▸ | F10 | P00742 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | C1R | P00736 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868318 | 0.88 | F7 (0.62) | F7F3F10KDM4EC1R | |
| SCHEMBL3257379 | 0.82 | KDM4E (0.61) | F7F3F10KDM4EC1R | |
| SCHEMBL31048496 | 0.82 | KDM4E (0.61) | F7F3F10KDM4EC1R | |
| SCHEMBL9867701 | 0.81 | NPC1 (0.58) | F7F3F10KDM4EC1R | |
| SCHEMBL220465 | 0.81 | ATM (0.50) | F7F3F10KDM4EKMT2A | |
| SCHEMBL13522987 | 0.81 | TOP2A (0.58) | F7F3F10KDM4EKMT2A | |
| SCHEMBL26833301 | 0.80 | ALDH1A1 (0.59) | F7F3F10KDM4EKMT2A | |
| SCHEMBL7394984 | 0.80 | F7 (1.00) | F7F3F10C1RKMT2A | |
| SCHEMBL9148638 | 0.77 | ALDH1A1 (0.63) | KDM4EKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9867803 | 0.76 | MAPT (0.56) | F7F3F10KDM4EC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |
| US-4131677-A | Anti-inflammatory oxazolo [5,4-b]pyridines | MERCK & CO., INC. (US) | 1978-12-26 | — | — | US | disclosed |
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |