Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | C1R | P00736 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868146 | 0.88 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL16459759 | 0.82 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL220465 | 0.81 | ATM (0.50) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL13522987 | 0.81 | TOP2A (0.58) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL9866729 | 0.81 | F7 (0.66) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL26833301 | 0.80 | ALDH1A1 (0.59) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL9148638 | 0.77 | ALDH1A1 (0.63) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL9867803 | 0.76 | MAPT (0.56) | NPC1RAB9ASMN1; SMN2MAPTC1R | |
| SCHEMBL30785580 | 0.74 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL9868132 | 0.74 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |