SCHEMBL9866855

SCHEMBL9866855

O=c1sc(CO)c(C(F)(F)F)n1CC=C(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9867861 0.81 ALDH1A1 (0.36) ALDH1A1HPGD
SCHEMBL9867854 0.81 ALDH1A1 (0.31) ALDH1A1HPGD
SCHEMBL9521058 0.72 KDM4E (0.47) ALDH1A1HPGD
SCHEMBL9521133 0.67 ALDH1A1 (0.31) ALDH1A1HPGD
SCHEMBL9521586 0.60 CYP3A4 (0.36) ALDH1A1
SCHEMBL1221770 0.47
SCHEMBL282080 0.46 DAO (0.31)
SCHEMBL22899080 0.45 CYP3A4 (0.48)
SCHEMBL9320567 0.45 SLC2A1 (0.30)
SCHEMBL4205700 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008281-A Insecticides, miticides, nematocides ROUSSEL UCLAF (FR) 1991-04-16 US disclosed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US disclosed