Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520403 | 0.82 | — | — | |
| SCHEMBL9866650 | 0.81 | POLB (0.52) | ALDH1A1HSD17B10MAPK1SMN1; SMN2POLB | |
| SCHEMBL10392131 | 0.78 | CYP3A4 (0.41) | CYP3A4SHMT2 | |
| SCHEMBL9521180 | 0.77 | CYP3A4 (0.37) | CYP3A4SHMT2POLB | |
| SCHEMBL10392132 | 0.76 | CYP3A4 (0.39) | CYP3A4SHMT2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9522954 | 0.76 | — | — | |
| SCHEMBL9519978 | 0.75 | NOTUM (0.36) | ALDH1A1POLBLMNA | |
| SCHEMBL9868309 | 0.74 | KDM4E (0.47) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL9519955 | 0.65 | POLB (0.43) | ALDH1A1SMN1; SMN2POLBKDM4ERAB9A | |
| SCHEMBL15484267 | 0.61 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10SMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |
| EP-0300898-A1 | Pyrethrinoid derivatives containing an N-heterocycle, processes and intermediates for their preparation, their use as pesticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-01-25 | — | — | EP | disclosed |