Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25540044 | 0.78 | MTNR1A (0.40) | MTNR1ABCL2BADGAAALDH1A1 | |
| SCHEMBL7823659 | 0.77 | PRKCD (0.49) | MTNR1ANOTUMMTNR1B | |
| SCHEMBL6099395 | 0.77 | PRKCD (0.49) | MTNR1ANOTUMMTNR1B | |
| SCHEMBL23761367 | 0.77 | PRKCD (0.49) | MTNR1ANOTUMMTNR1B | |
| SCHEMBL22248066 | 0.76 | NOTUM (0.46) | MTNR1ANOTUMMTNR1BGAAALDH1A1 | |
| SCHEMBL26208873 | 0.75 | MTNR1A (0.42) | MTNR1ANOTUMMTNR1B | |
| SCHEMBL19337132 | 0.75 | MTNR1A (0.46) | MTNR1ANOTUM | |
| SCHEMBL10193173 | 0.75 | MTNR1A (0.46) | MTNR1ANOTUM | |
| SCHEMBL5847276 | 0.75 | DRD2 (0.48) | MTNR1ANOTUMMTNR1BGAAALDH1A1 | |
| SCHEMBL5847274 | 0.75 | DRD2 (0.48) | MTNR1ANOTUMMTNR1BGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |