Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 17/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867296 | 1.00 | CTSD (0.60) | CTSDHDAC1HDAC6HDAC4 | |
| SCHEMBL24325178 | 0.81 | CTSD (0.51) | CTSD | |
| SCHEMBL29060359 | 0.81 | CTSD (0.51) | CTSD | |
| SCHEMBL24326475 | 0.81 | CTSD (0.51) | CTSD | |
| SCHEMBL9506108 | 0.77 | CTSD (0.41) | CTSD | |
| SCHEMBL9557524 | 0.77 | CTSD (0.41) | CTSD | |
| Hydrochloric Acid SCHEMBL10628796 | 0.76 | CTSD (0.40) | CTSD | |
| Hydrochloric Acid SCHEMBL9506267 | 0.76 | CTSD (0.40) | CTSD | |
| SCHEMBL14069032 | 0.75 | — | — | |
| SCHEMBL13969675 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061808-A | 2-oxo-1-pyrrolidine carboxylic acid esters | WARNER-LAMBERT COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4876343-A | Process for statine and statine analogs | WARNER-LAMBERT COMPANY (US) | 1989-10-24 | — | — | US | disclosed |