Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557524 | 1.00 | CTSD (0.41) | CTSDIRAK4ITGB3ITGB2ITGB1 | |
| Hydrochloric Acid SCHEMBL10628796 | 0.98 | CTSD (0.40) | CTSDIRAK4 | |
| Hydrochloric Acid SCHEMBL9506267 | 0.98 | CTSD (0.40) | CTSDIRAK4 | |
| SCHEMBL10460558 | 0.78 | — | — | |
| SCHEMBL9867293 | 0.77 | CTSD (0.60) | CTSD | |
| SCHEMBL9867296 | 0.77 | CTSD (0.60) | CTSD | |
| SCHEMBL21138065 | 0.73 | CTSD (0.39) | CTSDIRAK4 | |
| SCHEMBL12148580 | 0.73 | — | — | |
| SCHEMBL21057822 | 0.71 | CTSD (0.33) | CTSDITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL7329562 | 0.69 | CTSD (0.32) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198271-B1 | PEPTIDES | MERCK PATENT GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-5215966-A | For treatment of hypertension, hyperaldosteronism and cardiac insufficiency | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-06-01 | — | — | US | disclosed |
| US-4755592-A | Statine-containing peptides useful in medicaments | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-05 | — | — | US | disclosed |
| EP-0272444-A2 | Renin-inhibiting peptides | MERCK PATENT GmbH (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0198271-A2 | Peptides | MERCK PATENT GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |