Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646929 | 0.85 | ALDH1A1 (0.59) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9868757 | 0.82 | NPC1 (0.57) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7258548 | 0.81 | SMN1; SMN2 (1.00) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4600240 | 0.81 | KDM4E (0.68) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9646773 | 0.81 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11645613 | 0.81 | KDM4E (0.68) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13522986 | 0.81 | NPC1 (0.69) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL220575 | 0.81 | KDM4E (0.68) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| Iodide SCHEMBL11648822 | 0.79 | KDM4E (0.97) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| Iodide SCHEMBL11648817 | 0.79 | KDM4E (0.97) | KDM4ENPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |
| US-5061713-A | NO ANTIINFLAMMATORY ACTIVITY | SCIENCE ET ORGANIZATION (FR) | 1991-10-29 | — | — | US | disclosed |