Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11990709 | 0.78 | CES1 (0.43) | CES1CES2LMNAALDH1A1TP53 | |
| SCHEMBL6279642 | 0.78 | CES1 (0.42) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL9834930 | 0.72 | CA1 (0.43) | CES1CES2MAPTLMNAALDH1A1 | |
| SCHEMBL9834925 | 0.72 | CA1 (0.43) | CES1CES2MAPTLMNAALDH1A1 | |
| SCHEMBL8466102 | 0.69 | CES1 (0.39) | CES1CES2MAPTALDH1A1TP53 | |
| SCHEMBL7804736 | 0.67 | CA1 (0.48) | MAPTALDH1A1ATMCA1TSHR | |
| SCHEMBL27877068 | 0.66 | OPRM1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL7931836 | 0.65 | CES1 (0.42) | CES1CES2ALDH1A1TP53ATM | |
| SCHEMBL6275995 | 0.65 | CA2 (0.44) | ALDH1A1ATMCA1TSHRCYP3A4 | |
| SCHEMBL11043736 | 0.65 | CA1 (0.57) | MAPTTP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |