Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | UBE2M | P61081 | 1/20 | 0.55 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305400 | 0.86 | TSHR (0.80) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL11715149 | 0.86 | TSHR (0.80) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL17946287 | 0.85 | MEN1 (0.65) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL13503962 | 0.85 | KDM4E (0.84) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| Hydrochloric Acid SCHEMBL4618191 | 0.84 | MEN1 (0.63) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL25432112 | 0.82 | TSHR (0.70) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL10396663 | 0.82 | HPGD (0.74) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL30334082 | 0.82 | MEN1 (0.61) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL13503788 | 0.81 | KDM4E (0.61) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL21891709 | 0.81 | CPB1 (0.68) | MEN1KMT2ACYP2C9CYP2C19MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057611-A | Intermediates for analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-10-15 | — | — | US | disclosed |
| US-4833244-A | Ethanobenzazepines | HOECHST-ROUSEEL PHARMACEUTICALS INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4723009-A | USING 1-OXA-6-AZA SPIRO(2,5)OCTANE COMPOUNDS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-02-02 | — | — | US | disclosed |
| US-4654336-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0200052-A2 | Ethanobenzazepines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-11-05 | — | — | EP | disclosed |