Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867793 | 1.00 | KDM4E (0.34) | KDM4ECTSDLMNAALDH1A1GAA | |
| SCHEMBL4255299 | 0.75 | — | — | |
| SCHEMBL8394531 | 0.75 | — | — | |
| SCHEMBL27631766 | 0.74 | TGFBR1 (0.34) | ALDH1A1 | |
| SCHEMBL9868758 | 0.73 | ALDH1A1 (0.50) | KDM4ELMNAALDH1A1 | |
| SCHEMBL17742267 | 0.72 | — | — | |
| SCHEMBL5620325 | 0.72 | — | — | |
| SCHEMBL5620333 | 0.72 | — | — | |
| SCHEMBL2619427 | 0.72 | — | — | |
| SCHEMBL7609176 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |