Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867200 | 0.96 | HRH2 (0.53) | HRH2HRH3 | |
| SCHEMBL9866679 | 0.89 | PRMT5 (0.45) | HRH2HRH3 | |
| SCHEMBL9867806 | 0.85 | HRH2 (0.49) | HRH2HRH3 | |
| SCHEMBL10372620 | 0.83 | — | — | |
| SCHEMBL10372224 | 0.82 | HRH2 (0.48) | HRH2HRH3 | |
| SCHEMBL9867217 | 0.81 | HRH2 (0.48) | HRH2HRH3 | |
| SCHEMBL9867097 | 0.80 | KDM4E (0.50) | HRH2HRH3 | |
| SCHEMBL9867094 | 0.80 | KDM4E (0.48) | HRH2HRH3 | |
| SCHEMBL9867092 | 0.80 | KDM4E (0.48) | HRH2HRH3 | |
| Iodide SCHEMBL10755616 | 0.80 | HRH2 (0.61) | HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |