Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834167 | 0.81 | NPC1 (0.69) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL12755301 | 0.76 | NPC1 (0.75) | NPC1RAB9ALMNAKDM4EHPGD | |
| Drometrizole SCHEMBL15616 | 0.76 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EHPGD | |
| Drometrizole SCHEMBL29350665 | 0.76 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL3297579 | 0.76 | NPC1 (0.81) | NPC1RAB9ALMNAKDM4EHPGD | |
| Drometrizole SCHEMBL2548258 | 0.76 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EHPGD | |
| Drometrizole SCHEMBL27755727 | 0.76 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL11595106 | 0.74 | NPC1 (0.63) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL29813507 | 0.73 | NPC1 (0.71) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL561850 | 0.73 | NPC1 (0.71) | NPC1RAB9ALMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071995-A | Excellent ultraviolet absorbability for polyesters and polyamides; high thermal stability | KURARAY CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0363839-A1 | 2-hydroxyphenylbenzotriazol compounds and the use thereof | KURARAY CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |