Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672301 | 0.80 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL8724908 | 0.76 | CYP1A2 (0.53) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL9674925 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL9673792 | 0.72 | SMN1; SMN2 (0.76) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL9673128 | 0.71 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL2071589 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL13243006 | 0.71 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL15332932 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL13243011 | 0.70 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL24162675 | 0.70 | CYP1A2 (0.73) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036158-A | Intermediate compounds for an insecticidal and acaricidal pyrazole compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-30 | — | — | US | disclosed |
| US-5021446-A | Pyrazole compounds, insecticidal and acaricidal compositions and use | SUMITOMO CHEMICAL COMPANY (JP) | 1991-06-04 | — | — | US | disclosed |