Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673792 | 0.87 | SMN1; SMN2 (0.76) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL2071589 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL13243006 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL9672301 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL13243011 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL13243038 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL9671184 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL9672878 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL9671187 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL24162680 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357226-A1 | PREPARATION METHOD AND USE OF PYRAZOLE COMPOUND CONTAINING 1-(3,4-DIMETHOXYPHENYL)-BETA-CARBOLINE UNIT | NANTONG UNIVERSITY (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230357226-A1 | PREPARATION METHOD AND USE OF PYRAZOLE COMPOUND CONTAINING 1-(3,4-DIMETHOXYPHENYL)-BETA-CARBOLINE UNIT | NANTONG UNIVERSITY (CN) | 2023-11-09 | — | — | US | disclosed |
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4843068-A | INSECTICIDES, MITICIDES, FUNGICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0234045-A2 | A pyrazole oxime derivative and its production and use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357226-A1 | PREPARATION METHOD AND USE OF PYRAZOLE COMPOUND CONTAINING 1-(3,4-DIMETHOXYPHENYL)-BETA-CARBOLINE UNIT | DDC, AADAC, CDK7 | SMN1; SMN2 3362/4885CYP1A2 599/4885CYP2C19 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.