Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867988 | 1.00 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL10725331 | 0.87 | TAS1R3 (0.47) | ALDH1A1SMN1; SMN2CYP1A2ALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL10725329 | 0.87 | TAS1R3 (0.47) | ALDH1A1SMN1; SMN2CYP1A2ALOX15MAPK1 | |
| SCHEMBL13774772 | 0.83 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 | |
| SCHEMBL9866806 | 0.78 | HPGD (0.64) | SMN1; SMN2POLBTSHRHPGDALOX15 | |
| SCHEMBL31136182 | 0.78 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 | |
| SCHEMBL7416878 | 0.78 | POLB (0.56) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 | |
| SCHEMBL14381154 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 | |
| SCHEMBL5079207 | 0.77 | POLB (0.61) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 | |
| SCHEMBL5079211 | 0.77 | POLB (0.61) | ALDH1A1SMN1; SMN2POLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061808-A | 2-oxo-1-pyrrolidine carboxylic acid esters | WARNER-LAMBERT COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4876343-A | Process for statine and statine analogs | WARNER-LAMBERT COMPANY (US) | 1989-10-24 | — | — | US | disclosed |