Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822880 | 0.89 | PARP1 (0.32) | PARP1 | |
| Hydrochloric Acid SCHEMBL10807994 | 0.89 | BRD4 (0.37) | PARP1 | |
| SCHEMBL10805518 | 0.89 | PARP1 (0.35) | PARP1 | |
| SCHEMBL9822751 | 0.88 | ALDH1A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL9869193 | 0.88 | PARP1 (0.32) | PARP1 | |
| Methane SCHEMBL9867070 | 0.87 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL10810418 | 0.87 | PARP1 (0.32) | PARP1 | |
| SCHEMBL9866808 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL10808407 | 0.86 | PNMT (0.36) | PARP1 | |
| Hydrochloric Acid SCHEMBL10814166 | 0.86 | ALDH1A1 (0.33) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |