Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12910353 | 0.90 | NPC1 (0.81) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12910367 | 0.85 | NPC1 (0.73) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1675417 | 0.84 | NPC1 (0.73) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17391943 | 0.83 | NPC1 (0.71) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2249527 | 0.83 | RAB9A (0.71) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9155132 | 0.83 | NPC1 (1.00) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL941615 | 0.83 | NPC1 (0.71) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4143617 | 0.83 | NPC1 (0.71) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21249244 | 0.83 | NPC1 (0.70) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19380251 | 0.80 | NPC1 (0.70) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |
| US-5061713-A | NO ANTIINFLAMMATORY ACTIVITY | SCIENCE ET ORGANIZATION (FR) | 1991-10-29 | — | — | US | disclosed |