Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.83 |
| ▸ | NOS1 | P29475 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9270077 | 0.99 | TBXAS1 (0.81) | TBXAS1NOS1LMNAKDM4EMEN1 | |
| SCHEMBL6302832 | 0.95 | TBXAS1 (0.87) | TBXAS1NOS1LMNAMEN1KMT2A | |
| SCHEMBL3005716 | 0.91 | TBXAS1 (1.00) | TBXAS1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL22749387 | 0.88 | TBXAS1 (0.90) | TBXAS1NOS1LMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL9271328 | 0.86 | TBXAS1 (0.69) | TBXAS1NOS1LMNAKDM4EMEN1 | |
| SCHEMBL7685878 | 0.84 | NOS1 (0.81) | TBXAS1NOS1LMNAKDM4EMEN1 | |
| SCHEMBL9786288 | 0.83 | TBXAS1 (0.74) | TBXAS1NOS1LMNAKDM4E | |
| SCHEMBL9786317 | 0.83 | TBXAS1 (0.62) | TBXAS1NOS1LMNAKDM4EMEN1 | |
| SCHEMBL29980572 | 0.83 | TBXAS1 (0.91) | TBXAS1NOS1LMNAKDM4EMEN1 | |
| SCHEMBL7502648 | 0.83 | TBXAS1 (1.00) | TBXAS1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | claimed |