Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877022 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL9867945 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL1419962 | 0.64 | CA12 (0.56) | SMN1; SMN2MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL850295 | 0.64 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTHPGDALDH1A1TNF | |
| SCHEMBL1120541 | 0.63 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL28400515 | 0.63 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1GLANPC1RAB9A | |
| SCHEMBL8911435 | 0.62 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTPPARGALDH1A1GAA | |
| SCHEMBL31318741 | 0.62 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTPPARAHPGDKDM4E | |
| SCHEMBL6860586 | 0.62 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL3044572 | 0.61 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0321369-A1 | Heterocyclic sweeteners derived from N-carbamoyl-, N-thiocarbamoyl or N-amidino-glycine or beta-alanine | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1989-06-21 | — | — | EP | disclosed |