Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594794 | 0.80 | SLC6A2 (0.42) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL13534451 | 0.77 | ALOX5 (0.44) | SMN1; SMN2CYP4F2CYP4A11PPIDTBXAS1 | |
| SCHEMBL29723856 | 0.76 | MLYCD (0.46) | ALDH1A1KDM4ECYP1A2LMNACDC7 | |
| SCHEMBL850295 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPK1CYP4F2CYP4A11 | |
| SCHEMBL9554159 | 0.73 | LTA4H (0.51) | SMN1; SMN2ALDH1A1CYP4F2CYP4A11PPID | |
| SCHEMBL29264326 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MAPK1CYP4F2CYP4A11 | |
| SCHEMBL22119779 | 0.71 | OPRM1 (0.42) | SMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL31393600 | 0.71 | PLG (0.42) | SMN1; SMN2ALDH1A1KDM4EMAPK1GAA | |
| SCHEMBL27568133 | 0.71 | CA12 (0.42) | SMN1; SMN2ALDH1A1KDM4EMAPK1PPID | |
| SCHEMBL21821644 | 0.71 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1CYP4F2CYP4A11TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0321369-A1 | Heterocyclic sweeteners derived from N-carbamoyl-, N-thiocarbamoyl or N-amidino-glycine or beta-alanine | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1989-06-21 | — | — | EP | disclosed |