Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9868595 | 0.89 | HTR1A (0.49) | HTR1ASIGMAR1PARP1KDM4EALOX15 | |
| Oxalic Acid SCHEMBL9868038 | 0.89 | HTR1A (0.47) | HTR1ASIGMAR1PARP1S1PR1S1PR3 | |
| Oxalic Acid SCHEMBL9868441 | 0.88 | HTR1A (0.50) | HTR1ASIGMAR1PARP1KDM4EKMT2A | |
| Oxalic Acid SCHEMBL9867563 | 0.87 | HTR1A (0.51) | HTR1ASIGMAR1PARP1DRD3 | |
| SCHEMBL9867799 | 0.87 | HTR1A (0.51) | HTR1ASIGMAR1PARP1 | |
| SCHEMBL9867198 | 0.87 | HTR1A (0.53) | HTR1ASIGMAR1PARP1KDM4EALOX15 | |
| Oxalic Acid SCHEMBL9866814 | 0.87 | HTR1A (0.47) | HTR1ASIGMAR1PARP1KDM4EALOX15 | |
| SCHEMBL9868604 | 0.84 | HTR1A (0.54) | HTR1ASIGMAR1PARP1 | |
| Oxalic Acid SCHEMBL9867890 | 0.83 | HTR1A (0.53) | HTR1ASIGMAR1PARP1 | |
| SCHEMBL9867083 | 0.83 | HTR1A (0.55) | HTR1ASIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | disclosed |