Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9868595 | 0.98 | HTR1A (0.49) | HTR1AALDH1A1HPGDSIGMAR1PARP1 | |
| SCHEMBL9867198 | 0.92 | HTR1A (0.53) | HTR1ASIGMAR1PARP1 | |
| Oxalic Acid SCHEMBL9867563 | 0.88 | HTR1A (0.51) | HTR1ASIGMAR1PARP1 | |
| Oxalic Acid SCHEMBL9866814 | 0.88 | HTR1A (0.47) | HTR1ASIGMAR1PARP1 | |
| SCHEMBL9867083 | 0.88 | HTR1A (0.55) | HTR1ASIGMAR1PARP1 | |
| Oxalic Acid SCHEMBL9868441 | 0.87 | HTR1A (0.50) | HTR1AALDH1A1SIGMAR1PARP1 | |
| Oxalic Acid SCHEMBL9868440 | 0.87 | HTR1A (0.46) | HTR1ASIGMAR1PARP1 | |
| SCHEMBL9868604 | 0.87 | HTR1A (0.54) | HTR1ASIGMAR1PARP1 | |
| Oxalic Acid SCHEMBL9868038 | 0.86 | HTR1A (0.47) | HTR1ASIGMAR1PARP1 | |
| SCHEMBL9868497 | 0.85 | SIGMAR1 (0.50) | HTR1ASIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | claimed |
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | disclosed |