Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9865621 | 0.80 | HRH3 (0.46) | HRH3MAPK1USP2LMNA | |
| Hydrochloric Acid SCHEMBL9865627 | 0.80 | HRH3 (0.46) | HRH3MAPK1USP2LMNA | |
| Hydrochloric Acid SCHEMBL9866011 | 0.79 | DRD2 (0.44) | HRH3 | |
| Hydrochloric Acid SCHEMBL9866019 | 0.79 | DRD2 (0.44) | HRH3 | |
| SCHEMBL9866558 | 0.78 | HRH3 (0.45) | HRH3 | |
| Hydrochloric Acid SCHEMBL9602446 | 0.75 | MAPK14 (0.46) | HRH3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL9602451 | 0.75 | MAPK14 (0.46) | HRH3KCNH2HTR2A | |
| SCHEMBL10486917 | 0.74 | APP (0.41) | ALDH1A1LMNA | |
| Maleic Acid SCHEMBL9602897 | 0.71 | HRH3 (0.44) | HRH3KCNH2 | |
| Fumaric Acid SCHEMBL9602903 | 0.71 | HRH3 (0.44) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |