Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868641 | 1.00 | MMP3 (0.45) | MMP3MMP9POLBTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10721115 | 0.99 | TSHR (0.47) | MMP3MMP9POLBTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10721121 | 0.99 | TSHR (0.47) | MMP3MMP9POLBTSHRSMN1; SMN2 | |
| SCHEMBL6960913 | 0.82 | SMN1; SMN2 (0.64) | POLBTSHRSMN1; SMN2TP53TDP1 | |
| Hydrochloric Acid SCHEMBL7427148 | 0.81 | SMN1; SMN2 (0.62) | POLBTSHRSMN1; SMN2TP53TDP1 | |
| SCHEMBL7327060 | 0.79 | ALDH1A1 (0.50) | MMP3ALDH1A1RENMMP1 | |
| SCHEMBL14415361 | 0.79 | ALDH1A1 (0.50) | MMP3ALDH1A1RENMMP1 | |
| SCHEMBL9869819 | 0.79 | ALDH1A1 (0.50) | MMP3ALDH1A1RENMMP1 | |
| SCHEMBL12310327 | 0.79 | TSHR (0.58) | MMP3MMP9TSHRSMN1; SMN2TDP1 | |
| SCHEMBL7277453 | 0.79 | TSHR (0.58) | MMP3MMP9TSHRSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061808-A | 2-oxo-1-pyrrolidine carboxylic acid esters | WARNER-LAMBERT COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4876343-A | Process for statine and statine analogs | WARNER-LAMBERT COMPANY (US) | 1989-10-24 | — | — | US | disclosed |