SCHEMBL9868697

SCHEMBL9868697

O=C(Nc1cccnc1Cl)c1ccco1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.76
ALDH1A1 P00352 3/20 0.76
ALOX12 P18054 1/20 0.60
NPC1 O15118 4/20 0.59
KMT2A Q03164 4/20 0.59
MEN1 O00255 3/20 0.59
MAPT P10636 3/20 0.59
RECQL P46063 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
CYP1A2 P05177 1/20 0.58
MAPK1 P28482 1/20 0.58
KDM4E B2RXH2 2/20 0.58
POLB P06746 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
CASP6 P55212 1/20 0.58
CTDSP1 Q9GZU7 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
ESR2 Q92731 1/20 0.56
GAA P10253 1/20 0.55
HPGD P15428 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753825 0.80 MAPT (0.65) RAB9AALDH1A1NPC1KMT2AMEN1
SCHEMBL28302632 0.80 MAPT (0.65) RAB9AALDH1A1NPC1KMT2AMEN1
SCHEMBL30117825 0.78 RAB9A (0.74) RAB9AALDH1A1NPC1KMT2AMEN1
SCHEMBL6632751 0.78 RAB9A (0.74) RAB9AALDH1A1NPC1KMT2AMEN1
SCHEMBL9538774 0.78 RAB9A (0.69) RAB9AALDH1A1NPC1MAPTSMN1; SMN2
SCHEMBL8299753 0.76 TDP1 (0.68) RAB9AALDH1A1ALOX12NPC1KMT2A
SCHEMBL30117873 0.75 RAB9A (0.79) RAB9AALDH1A1NPC1KMT2AMEN1
SCHEMBL3096372 0.75 RAB9A (0.79) RAB9AALDH1A1NPC1KMT2AMEN1
SCHEMBL30943984 0.74 GFER (0.63) RAB9AALDH1A1ALOX12NPC1KMT2A
SCHEMBL7450576 0.74 NPC1 (1.00) RAB9AALDH1A1ALOX12NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5077408-A PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS SCIENCE ET ORGANISATION (FR) 1991-12-31 US disclosed