SCHEMBL331769

SCHEMBL331769

NC(=O)[C@@]1(n2ccc(N)nc2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.49
PDE3A Q14432 3/20 0.49
MTOR P42345 2/20 0.49
PDE4D Q08499 1/20 0.49
SLC29A1 Q99808 1/20 0.49
THRB P10828 1/20 0.49
MDM2 Q00987 1/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
CACNA1F O60840 2/20 0.37
ALB P02768 2/20 0.37
MAPT P10636 2/20 0.37
CACNA1D Q01668 2/20 0.37
CACNA1S Q13698 2/20 0.37
CACNA1C Q13936 2/20 0.37
PYGB P11216 2/20 0.35
POLA1 P09884 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30514303 0.92 LMNA (0.50) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL26666720 0.91 LMNA (0.49) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL236109 0.89 PDE3A (0.48) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL29773194 0.86 PDE3A (0.46) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL10612101 0.86 PDE3A (0.46) LMNAPDE3AMTORPDE4DSLC29A1
Phosphoric Acid SCHEMBL21465061 0.85 PDE3A (0.45) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL30584639 0.85 PDE3A (0.45) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL441998 0.85 PDE3A (0.45) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL6060509 0.85 PDE3A (0.45) LMNAPDE3AMTORPDE4DSLC29A1
SCHEMBL9667470 0.85 PDE3A (0.44) LMNAPDE3AMTORPDE4DSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097706-B2 Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein Hammi Holdings Co., Ltd (KR) 2012-01-17 US claimed
CN-101861320-A Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein HANMI PHARM IND CO LTD 2010-10-13 CN claimed
US-20100249395-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN HANMI PHARM. CO., LTD. (KR) 2010-09-30 US claimed
EP-2220090-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN Hanmi Pharm. Co., Ltd. (KR) 2010-08-25 EP claimed
WO-2009066892-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN HANMI PHARM. CO., LTD. (KR) 2009-05-28 WO claimed
US-20250283094-A1 Modified Nucleosides SOMALOGIC OPERATING CO., INC. (US) 2025-09-11 US disclosed
US-20240158833-A1 Compositions and Methods for Labeling Modified Nucleotides in Nucleic Acids NEW ENGLAND BIOLABS, INC. (US) 2024-05-16 US disclosed
CN-111542523-B Heterocyclic compounds as PRMT5 inhibitors 朱比连特埃皮斯科瑞有限责任公司 2024-03-29 CN disclosed
EP-4323374-A1 MODIFIED NUCLEOSIDES SomaLogic Operating Co., Inc. (US) 2024-02-21 EP disclosed
EP-4294936-A1 COMPOSITIONS AND METHODS FOR LABELING MODIFIED NUCLEOTIDES IN NUCLEIC ACIDS New England Biolabs, Inc. (US) 2023-12-27 EP disclosed
CN-117242085-A Modified nucleosides 私募蛋白质体操作有限公司 2023-12-15 CN disclosed
CN-116925993-A Genetically engineered strains and methods for enzyme-catalyzed production of cytidine acids 北京量维生物科技研究院有限公司 2023-10-24 CN disclosed
WO-2022178093-A1 COMPOSITIONS AND METHODS FOR LABELING MODIFIED NUCLEOTIDES IN NUCLEIC ACIDS NEW ENGLAND BIOLABS, INC. (US) 2022-08-25 WO disclosed
US-8097706-B2 Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein Hammi Holdings Co., Ltd (KR) 2012-01-17 US disclosed
CN-101861320-A Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein HANMI PHARM IND CO LTD 2010-10-13 CN disclosed
US-20100249395-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN HANMI PHARM. CO., LTD. (KR) 2010-09-30 US disclosed
EP-2220090-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN Hanmi Pharm. Co., Ltd. (KR) 2010-08-25 EP disclosed
WO-2009066892-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN HANMI PHARM. CO., LTD. (KR) 2009-05-28 WO disclosed
EP-1140967-A1 TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2001-10-10 EP disclosed
WO-2000039145-A1 TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250283094-A1 Modified Nucleosides NT5C3B, PNP, TYMP LMNA 1230/4885PDE3A 1392/4885MTOR 4515/4885
US-20100249395-A1 METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN TYMP, SI, DPYD LMNA 3050/4885PDE3A 2731/4885MTOR 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.