Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321087 | 0.93 | EPHX1 (0.56) | EPHX1KDM4ELMNAEPHX2DPP7 | |
| SCHEMBL9868895 | 0.91 | EPHX1 (0.59) | EPHX1EPHX2DPP7PLA2G2APLA2G4A | |
| SCHEMBL9868236 | 0.91 | EPHX1 (0.59) | EPHX1EPHX2DPP7PLA2G2APLA2G4A | |
| SCHEMBL6129741 | 0.88 | EPHX1 (0.61) | EPHX1EPHX2ACHEMMP2PLA2G2A | |
| SCHEMBL9866601 | 0.86 | CTSD (0.48) | EPHX1ALOX15KDM4ELMNAMMP2 | |
| SCHEMBL3257790 | 0.80 | EPHX1 (0.68) | EPHX1EPHX2DPP7PLA2G2APLA2G4A | |
| SCHEMBL23862431 | 0.79 | EPHX1 (0.52) | EPHX1EPHX2ACHEMMP2PLA2G2A | |
| SCHEMBL1264732 | 0.79 | EPHX1 (0.52) | EPHX1ALOX15EPHX2ACHEMMP2 | |
| SCHEMBL6935602 | 0.79 | — | — | |
| SCHEMBL18885000 | 0.79 | ACHE (0.53) | EPHX1EPHX2ACHEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| EP-0126326-B1 | PROCESS FOR PREPARING 1,2,4-TRIAZOLE-3-CARBOXAMIDES | UBE INDUSTRIES, LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| US-4578479-A | Process for preparing 1,2,4-triazole-3-carboxamides | UBE INDUSTRIES, LTD. (JP) | 1986-03-25 | — | — | US | disclosed |
| EP-0126326-A1 | Process for preparing 1,2,4-triazole-3-carboxamides | UBE INDUSTRIES, LTD. (JP) | 1984-11-28 | — | — | EP | disclosed |