Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22731662 | 0.80 | CYP2D6 (0.35) | — | |
| SCHEMBL20761563 | 0.77 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL22719858 | 0.75 | GPR119 (0.31) | — | |
| SCHEMBL12901515 | 0.75 | CYP3A4 (0.43) | — | |
| SCHEMBL9869102 | 0.74 | — | — | |
| SCHEMBL14534168 | 0.74 | CRBN (0.40) | SIGMAR1 | |
| SCHEMBL20762592 | 0.73 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL27105201 | 0.73 | — | — | |
| SCHEMBL12901469 | 0.72 | GPR119 (0.49) | — | |
| SCHEMBL25159789 | 0.72 | GPR119 (0.37) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073560-A | SPIRO-ISOXAZOLIDINE DERIVATIVES AS CHOLINERGIC AGENTS | FISONS CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |