Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5946046 | 0.88 | ALDH1A1 (0.37) | PAOXHRH3DRD3RAB9ANPC1 | |
| SCHEMBL5946007 | 0.83 | HRH3 (0.46) | HRH3ALDH1A1KDM4ERAD52 | |
| SCHEMBL5251321 | 0.82 | HRH3 (0.50) | HRH3RAD52 | |
| SCHEMBL5546345 | 0.78 | CXCR4 (0.46) | HRH3RAB9ANPC1ALDH1A1SIGMAR1 | |
| SCHEMBL9869778 | 0.78 | KEAP1 (0.48) | HRH3ALDH1A1USP2HPGDSIGMAR1 | |
| SCHEMBL11606849 | 0.77 | PAOX (0.34) | PAOXALDH1A1KDM4E | |
| SCHEMBL8561716 | 0.76 | HRH3 (0.54) | HRH3 | |
| SCHEMBL84799 | 0.74 | HRH3 (0.46) | PAOXHRH3DRD3RAB9ANPC1 | |
| SCHEMBL5544470 | 0.73 | CXCR4 (0.47) | HRH3RAB9ANPC1ALDH1A1SIGMAR1 | |
| SCHEMBL15133512 | 0.72 | HRH3 (0.45) | PAOXHRH3DRD3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |