SCHEMBL9869042

SCHEMBL9869042

CCC(C)(C)c1ccc(OCCCC(=O)Nc2ccc([O])cc2)c(C(C)(C)CC)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
MAPK1 P28482 5/20 0.54
NPSR1 Q6W5P4 5/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
ALDH1A1 P00352 2/20 0.54
MAPT P10636 5/20 0.47
HTT P42858 4/20 0.47
UBE2N P61088 2/20 0.47
GLA P06280 1/20 0.47
MITF O75030 1/20 0.47
POLB P06746 1/20 0.44
RAD52 P43351 2/20 0.44
STAT3 P40763 1/20 0.44
RCE1 Q9Y256 1/20 0.44
APAF1 O14727 1/20 0.44
HSP90AA1 P07900 1/20 0.44
RAB9A P51151 1/20 0.44
NOD2 Q9HC29 1/20 0.44
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568652 0.84 MEN1 (0.48) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL8616192 0.84 MEN1 (0.46) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL5675715 0.84 RAB9A (0.48) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL11624748 0.84 MEN1 (0.46) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL10833283 0.83 MEN1 (0.47) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL8621068 0.83 HIF1A (0.52) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL10906826 0.83 SMN1; SMN2 (0.57) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL10906825 0.83 HIF1A (0.52) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL11001352 0.83 MEN1 (0.47) MEN1KMT2AMAPK1NPSR1SMN1; SMN2
SCHEMBL11001355 0.83 MEN1 (0.47) MEN1KMT2AMAPK1NPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051342-A Sharpness, whiteness FUJI PHOTO FILM CO., LTD. (JP) 1991-09-24 US disclosed