Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | UBE2N | P61088 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624748 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL5675715 | 0.85 | RAB9A (0.48) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL9869042 | 0.84 | MEN1 (0.54) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL8656152 | 0.84 | MAPK1 (0.44) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL9340282 | 0.83 | RAB9A (0.44) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL8616192 | 0.83 | MEN1 (0.46) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL10833283 | 0.83 | MEN1 (0.47) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL9491257 | 0.82 | MEN1 (0.43) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL9550874 | 0.82 | MAPK1 (0.44) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL7698979 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAPK1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |