Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585963 | 0.75 | KDM4E (0.39) | MAPK1ALDH1A1GAAKDM4ELMNA | |
| SCHEMBL9870200 | 0.74 | L3MBTL1 (0.52) | MAPTALDH1A1GAAAHRKDM4E | |
| SCHEMBL7196085 | 0.68 | — | — | |
| SCHEMBL17967795 | 0.65 | MAPT (0.38) | MAPK1CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL11433888 | 0.65 | HCAR2 (0.37) | MAPK1CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL1897762 | 0.64 | GRM4 (0.38) | MAPK1CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL6313709 | 0.64 | CHRNB2 (0.38) | MAPK1CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL13485374 | 0.64 | — | — | |
| SCHEMBL15360097 | 0.64 | — | — | |
| SCHEMBL7078201 | 0.64 | MAPT (0.49) | MAPK1MAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988712-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4882344-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-11-21 | — | — | US | disclosed |
| US-4803277-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-02-07 | — | — | US | disclosed |