Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866361 | 0.87 | KMT2A (0.35) | KDM4EMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9865871 | 0.86 | L3MBTL1 (0.41) | SMN1; SMN2KMT2ATDP1L3MBTL1TSHR | |
| SCHEMBL10374044 | 0.84 | SMN1; SMN2 (0.36) | KDM4EMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9867797 | 0.77 | MEN1 (0.33) | KMT2AL3MBTL1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9869217 | 0.74 | KDM4E (0.33) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9866776 | 0.73 | SMN1; SMN2 (0.37) | KDM4EMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9866582 | 0.73 | BCHE (0.40) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL12319048 | 0.70 | LOX (0.41) | MAPTKMT2AHSD17B10MEN1LMNA | |
| SCHEMBL11812003 | 0.68 | TDP1 (0.53) | KDM4ESMN1; SMN2KMT2ATDP1HSD17B10 | |
| SCHEMBL9289307 | 0.67 | TDP1 (0.59) | KDM4EMAPTSMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |